prikaz prve stranice dokumenta The effect of nickel ions on the susceptibility of bacteria to ciprofloxacin and ampicillin
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Scientific paper - Original scientific paper
The effect of nickel ions on the susceptibility of bacteria to ciprofloxacin and ampicillin
Folia Microbiologica, 67 (2022), 4; 649-657. https://doi.org/10.1007/s12223-022-00960-x
Pavlić, Andrej; Gobin, Ivana; Begić, Gabrijela; Tota, Marin; Abram, Maja; Špalj, Stjepan

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Pavlić, A., Gobin, I., Begić, G., Tota, M., Abram, M. & Špalj, S. (2022). The effect of nickel ions on the susceptibility of bacteria to ciprofloxacin and ampicillin. Folia Microbiologica, 67. (4), 649-657. doi: 10.1007/s12223-022-00960-x

Pavlić, Andrej, et al. "The effect of nickel ions on the susceptibility of bacteria to ciprofloxacin and ampicillin." Folia Microbiologica, vol. 67, no. 4, 2022, pp. 649-657. https://doi.org/10.1007/s12223-022-00960-x

Pavlić, Andrej, Ivana Gobin, Gabrijela Begić, Marin Tota, Maja Abram and Stjepan Špalj. "The effect of nickel ions on the susceptibility of bacteria to ciprofloxacin and ampicillin." Folia Microbiologica 67, no. 4 (2022): 649-657. https://doi.org/10.1007/s12223-022-00960-x

Pavlić, A., et al. (2022) 'The effect of nickel ions on the susceptibility of bacteria to ciprofloxacin and ampicillin', Folia Microbiologica, 67(4), pp. 649-657. doi: 10.1007/s12223-022-00960-x

Pavlić A, Gobin I, Begić G, Tota M, Abram M, Špalj S. The effect of nickel ions on the susceptibility of bacteria to ciprofloxacin and ampicillin. Folia Microbiologica [Internet]. 2022 March 30 [cited 2024 April 28];67(4):649-657. doi: 10.1007/s12223-022-00960-x

A. Pavlić, I. Gobin, G. Begić, M. Tota, M. Abram and S. Špalj, "The effect of nickel ions on the susceptibility of bacteria to ciprofloxacin and ampicillin", Folia Microbiologica, vol. 67, no. 4, pp. 649-657, March 2022. [Online]. Available at: https://urn.nsk.hr/urn:nbn:hr:271:894314. [Accessed: 28 April 2024]

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Metadata
Title (english)The effect of nickel ions on the susceptibility of bacteria to ciprofloxacin and ampicillin
AuthorAndrej Pavlić
AuthorIvana Gobin
AuthorGabrijela Begić
AuthorMarin Tota
AuthorMaja Abram
AuthorStjepan Špalj
Author's institutionUniversity of Rijeka
(Faculty of Dental Medicine)
Scientific / art field,
discipline and subdiscipline		BIOMEDICINE AND HEALTHCARE
Dental Medicine
Scientific / art field,
discipline and subdiscipline		BIOMEDICINE AND HEALTHCARE
Clinical Medical Sciences
Medical Microbiology
Abstract (english)
To explore the interaction effects of ciprofloxacin and ampicillin with nickel on the growth of bacteria, Staphylococcus aureus strain ATCC 29213, Enterococcus faecalis ATCC 29212 and Escherichia coli ATCC 25922 were used. Minimum inhibitory concentrations (MICs) were determined for nickel, ciprofloxacin and ampicillin, and the checkerboard method was used to assess their cumulative effects on bacterial growth. The interactions between the metal and antibiotics were assessed by the fractional inhibitory concentration (FIC). The MICs for ciprofloxacin and ampicillin were 0.31 and 1 mg/L for E. faecalis, 0.62 and 1 mg/L for S. aureus and 0.005 and 2.5 for E. coli, respectively. The MIC for nickel was 1000 mg/L for all bacteria. The FIC results for ciprofloxacin and nickel demonstrated an antagonistic effect of the two agents on the growth of E. coli and E. faecalis and an additive effect on S. aureus. The FICs for ampicillin and nickel demonstrated a synergistic effect on the growth of E. faecalis and E. coli. Different interactions of metals and antibiotics were observed depending on the bacteria and the type of antibiotic.
Keywords (english)
Languageenglish
Publication typeScientific paper - Original scientific paper
Publication statusPublished
Peer reviewPeer review - international
Publication versionPublished version
Journal titleFolia Microbiologica
Numberingvol. 67, no. 4, pp. 649-657
p-ISSN0015-5632
e-ISSN1874-9356
DOIhttps://doi.org/10.1007/s12223-022-00960-x
URN:NBNurn:nbn:hr:271:894314
Publication2022-03-30
Document URLhttps://link.springer.com/10.1007/s12223-022-00960-x
Type of resourceText
Access conditionsRestricted access
Terms of useLicence In copyright icon
Created on2023-01-19 09:06:50