prikaz prve stranice dokumenta Assessment of internal derangement of the temporomandibular joint according to the concentration of salivary cytokines in patients with spondyloarthritis
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Scientific paper - Original scientific paper
Assessment of internal derangement of the temporomandibular joint according to the concentration of salivary cytokines in patients with spondyloarthritis
Medical Hypotheses, 170 (2023); 111000. https://doi.org/10.1016/j.mehy.2022.111000
Laškarin, Ana-Marija: Laškarin; Kehler, Tatjana; Gržić, Renata; Dulčić, Nikša

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Laškarin, A. M. L., Kehler, T., Gržić, R. & Dulčić, N. (2023). Assessment of internal derangement of the temporomandibular joint according to the concentration of salivary cytokines in patients with spondyloarthritis. Medical Hypotheses, 170.. doi: 10.1016/j.mehy.2022.111000

Laškarin, Ana Marija: Laškarin, et al. "Assessment of internal derangement of the temporomandibular joint according to the concentration of salivary cytokines in patients with spondyloarthritis." Medical Hypotheses, vol. 170, 2023. https://doi.org/10.1016/j.mehy.2022.111000

Laškarin, Ana Marija: Laškarin, Tatjana Kehler, Renata Gržić and Nikša Dulčić. "Assessment of internal derangement of the temporomandibular joint according to the concentration of salivary cytokines in patients with spondyloarthritis." Medical Hypotheses 170 (2023). https://doi.org/10.1016/j.mehy.2022.111000

Laškarin, A. M. L., et al. (2023) 'Assessment of internal derangement of the temporomandibular joint according to the concentration of salivary cytokines in patients with spondyloarthritis', Medical Hypotheses, 170. doi: 10.1016/j.mehy.2022.111000

Laškarin AML, Kehler T, Gržić R, Dulčić N. Assessment of internal derangement of the temporomandibular joint according to the concentration of salivary cytokines in patients with spondyloarthritis. Medical Hypotheses [Internet]. 2023 January [cited 2024 May 15];170. doi: 10.1016/j.mehy.2022.111000

A. M. L. Laškarin, T. Kehler, R. Gržić and N. Dulčić, "Assessment of internal derangement of the temporomandibular joint according to the concentration of salivary cytokines in patients with spondyloarthritis", Medical Hypotheses, vol. 170, January 2023. [Online]. Available at: https://urn.nsk.hr/urn:nbn:hr:271:633700. [Accessed: 15 May 2024]

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Metadata
Title (english)Assessment of internal derangement of the temporomandibular joint according to the concentration of salivary cytokines in patients with spondyloarthritis
AuthorAna-Marija: Laškarin Laškarin
AuthorTatjana Kehler
AuthorRenata Gržić
AuthorNikša Dulčić
Author's institutionUniversity of Rijeka
(Faculty of Dental Medicine)
Scientific / art field,
discipline and subdiscipline		BIOMEDICINE AND HEALTHCARE
Dental Medicine
Scientific / art field,
discipline and subdiscipline		BIOMEDICINE AND HEALTHCARE
Basic Medical Sciences
Abstract (english)
Spondyloarthritis (SpA) is a group of autoinflammatory/autoimmune diseases that affects the spine and pe-ripheral joints. Involvement of the cervical spine correlates with occurrence of temporomandibular disorders (TMDs). Proinflammatory cytokines, interleukin (IL)-23, IL-17A, and tumour necrosis factor-alpha (TNF-alpha) are significantly involved in the immunopathogenesis of SpA, and inflammation is one of the causes of TMDs. We hypothesised that internal derangement (ID) of temporomandibular joints (TMJs), as the most frequent TMDs in patients with SpA, could be associated with salivary pro-inflammatory markers and clinical activity of axial SpA, measured with laboratory methods or rheumatological indexes. If a statistically significant difference in the concentration of salivary IL-23, IL-17A or TNF-alpha exists between patients with symptomatic or asymptomatic ID and patients without TMDs, the diagnostic accuracy of certain cytokine(s) for ID can be calculated. The diag-nostic accuracy of the cytokine(s) could emphasise the inflammatory background of ID and possibly broaden therapeutic approaches for symptomatic ID in patients with SpA with biological drugs in addition to the routine application of occlusal splint and/or physical therapy.
Keywords (english)
Languageenglish
Publication typeScientific paper - Original scientific paper
Publication statusPublished
Peer reviewPeer review - international
Publication versionPublished version
Journal titleMedical Hypotheses
Numberingvol. 170, 111000
p-ISSN0306-9877
DOIhttps://doi.org/10.1016/j.mehy.2022.111000
URN:NBNurn:nbn:hr:271:633700
Publication2023-01
Document URLhttps://linkinghub.elsevier.com/retrieve/pii/S0306987722002407
Type of resourceText
Access conditionsInstitutional access
Terms of useLicence In copyright icon
Created on2024-01-17 10:59:43