prikaz prve stranice dokumenta The Influence of Hyaluronic Acid Adjunctive Therapy of Periodontitis on Salivary Markers of Oxidative Stress: Randomized, Controlled Clinical Trial
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Scientific paper - Original scientific paper
The Influence of Hyaluronic Acid Adjunctive Therapy of Periodontitis on Salivary Markers of Oxidative Stress: Randomized, Controlled Clinical Trial
Antioxidants, 11 (2022), 1; 135. https://doi.org/10.3390/antiox11010135
Olszewska-Czyz, Iwona; Kralik, Kristina; Tota, Marin; Prpić, Jelena

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Olszewska Czyz, I., Kralik, K., Tota, M. & Prpić, J. (2022). The Influence of Hyaluronic Acid Adjunctive Therapy of Periodontitis on Salivary Markers of Oxidative Stress: Randomized, Controlled Clinical Trial. Antioxidants, 11. (1). doi: 10.3390/antiox11010135

Olszewska Czyz, Iwona, et al. "The Influence of Hyaluronic Acid Adjunctive Therapy of Periodontitis on Salivary Markers of Oxidative Stress: Randomized, Controlled Clinical Trial." Antioxidants, vol. 11, no. 1, 2022. https://doi.org/10.3390/antiox11010135

Olszewska Czyz, Iwona, Kristina Kralik, Marin Tota and Jelena Prpić. "The Influence of Hyaluronic Acid Adjunctive Therapy of Periodontitis on Salivary Markers of Oxidative Stress: Randomized, Controlled Clinical Trial." Antioxidants 11, no. 1 (2022). https://doi.org/10.3390/antiox11010135

Olszewska Czyz, I., et al. (2022) 'The Influence of Hyaluronic Acid Adjunctive Therapy of Periodontitis on Salivary Markers of Oxidative Stress: Randomized, Controlled Clinical Trial', Antioxidants, 11(1). doi: 10.3390/antiox11010135

Olszewska Czyz I, Kralik K, Tota M, Prpić J. The Influence of Hyaluronic Acid Adjunctive Therapy of Periodontitis on Salivary Markers of Oxidative Stress: Randomized, Controlled Clinical Trial. Antioxidants [Internet]. 2022 January 07 [cited 2024 December 23];11(1). doi: 10.3390/antiox11010135

I. Olszewska Czyz, K. Kralik, M. Tota and J. Prpić, "The Influence of Hyaluronic Acid Adjunctive Therapy of Periodontitis on Salivary Markers of Oxidative Stress: Randomized, Controlled Clinical Trial", Antioxidants, vol. 11, no. 1, January 2022. [Online]. Available at: https://urn.nsk.hr/urn:nbn:hr:271:251718. [Accessed: 23 December 2024]

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Metadata
Title (english)The Influence of Hyaluronic Acid Adjunctive Therapy of Periodontitis on Salivary Markers of Oxidative Stress: Randomized, Controlled Clinical Trial
AuthorIwona Olszewska-Czyz
AuthorKristina Kralik
AuthorMarin Tota
AuthorJelena Prpić
Author's institutionUniversity of Rijeka
(Faculty of Dental Medicine)
Scientific / art field,
discipline and subdiscipline		BIOMEDICINE AND HEALTHCARE
Dental Medicine
Periodontology
Abstract (english)
Periodontitis is a common oral disease affecting the tooth-supporting tissues. Bacteria have been long viewed as the main causative factor in its development; however, many investigations have proved that aberrant immune and inflammatory response and the resulting misbalance between the damage caused by reactive oxygen species and the antioxidant capacity of tissues may be an underlying factor in disease progression that reduces healing potential. The objective of the current trial is to assess the outcomes of the addition of hyaluronic acid (HA) to standard non-surgical periodontal therapy (NST) on some major oxidative stress markers in saliva. HA-based gel designed for dental application was used and the measurements were taken after 3 months. HA adjunctive therapy had a significantly greater increase in markers with antioxidant properties as well as total antioxidant capacity compared to standard NST alone. Furthermore, clinically measured levels of gingival inflammation (bleeding on probing-BOP) and periodontal destruction (clinical attachment loss-CAL) were significantly correlated with these markers, and the correlation was negative. This investigation demonstrates that HA may indeed express antioxidant properties and improve the antioxidant capacity of periodontal tissues, thus improving the prognosis for the teeth and the results of periodontal therapy. Further investigations will be necessary to determine the duration of these effects over time.
Keywords (english)
Languageenglish
Publication typeScientific paper - Original scientific paper
Publication statusPublished
Peer reviewPeer review - international
Publication versionPublished version
Journal titleAntioxidants
Numberingvol. 11, no. 1, 135
e-ISSN2076-3921
DOIhttps://doi.org/10.3390/antiox11010135
URN:NBNurn:nbn:hr:271:251718
Publication2022-01-07
Document URLhttps://www.mdpi.com/2076-3921/11/1/135
Type of resourceText
Access conditionsOpen access
Terms of useLicence Attribution 4.0 International (CC BY 4.0) icon
Created on2023-01-19 10:21:28