prikaz prve stranice dokumenta Osteonekroza čeljusti uzrokovana lijekovima i zračenjem
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master's thesis
Osteonekroza čeljusti uzrokovana lijekovima i zračenjem
diplomski rad
2024. urn:nbn:hr:271:465092
Mihalić, Dajana
University of Rijeka
Faculty of Dental Medicine

Cite this document

Mihalić, D. (2024). Osteonekroza čeljusti uzrokovana lijekovima i zračenjem : diplomski rad (Master's thesis). Rijeka: University of Rijeka. Retrieved from https://urn.nsk.hr/urn:nbn:hr:271:465092

Mihalić, Dajana. "Osteonekroza čeljusti uzrokovana lijekovima i zračenjem : diplomski rad." Master's thesis, University of Rijeka, 2024. https://urn.nsk.hr/urn:nbn:hr:271:465092

Mihalić, Dajana. "Osteonekroza čeljusti uzrokovana lijekovima i zračenjem : diplomski rad." Master's thesis, University of Rijeka, 2024. https://urn.nsk.hr/urn:nbn:hr:271:465092

Mihalić, D. (2024). 'Osteonekroza čeljusti uzrokovana lijekovima i zračenjem : diplomski rad', Master's thesis, University of Rijeka, accessed 16 December 2024, https://urn.nsk.hr/urn:nbn:hr:271:465092

Mihalić D. Osteonekroza čeljusti uzrokovana lijekovima i zračenjem : diplomski rad [Master's thesis]. Rijeka: University of Rijeka; 2024 [cited 2024 December 16] Available at: https://urn.nsk.hr/urn:nbn:hr:271:465092

D. Mihalić, "Osteonekroza čeljusti uzrokovana lijekovima i zračenjem : diplomski rad", Master's thesis, University of Rijeka, Rijeka, 2024. Available at: https://urn.nsk.hr/urn:nbn:hr:271:465092

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Metadata
TitleOsteonekroza čeljusti uzrokovana lijekovima i zračenjem : diplomski rad
Title (english)Medication related osteonecrosis and osteoradionecrosis of the jaw : graduate thesis
AuthorDajana Mihalić
MentorMiranda Muhvić Urek (mentor)
Committee memberMiranda Muhvić Urek (predsjednik povjerenstva)
Committee memberSonja Pezelj-Ribarić (član povjerenstva)
Committee memberAlen Braut (član povjerenstva)
GranterUniversity of Rijeka
(Faculty of Dental Medicine)
Rijeka
Defense date and country2024, Croatia
Scientific / art field,
discipline and subdiscipline		BIOMEDICINE AND HEALTHCARE
Dental Medicine
Abstract
Osteonekroza čeljusti uzrokovana lijekovima (MRONJ) i osteoradionekroza čeljusti (ORN) su dva različita medicinska pojma sa relativno istom kliničkom slikom. Glavno obilježje obje bolesti je pojava eksponirane nekrotične kosti. MRONJ nastaje uslijed terapije antiresorptivnim i antiangiogenim lijekovima, dok osteoradionekrozu uzrokuje radioterapija u području glave i vrata. U postavljanju dijagnoze bitno je provesti dobru anamnezu, klinički pregled i dodatne radiološke pretrage. Istraživanja su pokazala kako dobra oralna higijena, antibiotska terapija, hiperbarična oksigenoterapija, terapija trombocitima obogaćenim fibrinom te kirurške resekcije i debridmani postižu najbolje cijeljenje nekrotičnih područja. Iako se bolesti razlikuju u mnogim karakteristikama ono što ih povezuje je potreba za osvješćivanjem doktora dentalne, ali i opće medicine o faktorima rizika za nastanak bolesti te o njihovoj prevenciji.
Abstract (english)
Medication related osteonecrosis of the jaw (MRONJ) and osteoradionecrosis of the jaw (ORNJ) are two different diseases, but with qiuite similar appearance. They both are presented as an exposed necrotic bone. MRONJ occures due to antiresorptive and antiangiogenic drug therapy and ORNJ due to the radiotherapy of head and neck. In making a diagnosis, it is important to conduct a good medical history, clinical examination and additional radiological analysis. Studies have shown that good oral hygiene, antibiotic therapy, hyperbaric oxygen therapy, platelet-rich fibrin procedures, surgical resections and debridements achieve the best healing of necrotic areas. Although both diseases differ in many characteristics, what connects them is the need to raise awereness within medical circles about the risk factors for the occurrence of the diseases and their prevention.
Keywords
Keywords (english)
Languagecroatian
URN:NBNurn:nbn:hr:271:465092
Study programmeTitle: Dental Medicine
Study programme type: university
Study level: integrated undergraduate and graduate
Academic / professional title: doktor/doktorica dentalne medicine (doktor/doktorica dentalne medicine)
Type of resourceText
File originBorn digital
Access conditionsAccess restricted to students and staff of home institution
Terms of useLicence In copyright icon
Created on2024-06-26 10:18:31