prikaz prve stranice dokumenta Biomolecules in Dental Applications: Randomized, Controlled Clinical Trial Evaluating the Influence of Hyaluronic Acid Adjunctive Therapy on Clinical Parameters of Moderate Periodontitis
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Biomolecules in Dental Applications: Randomized, Controlled Clinical Trial Evaluating the Influence of Hyaluronic Acid Adjunctive Therapy on Clinical Parameters of Moderate Periodontitis
Biomolecules, 11 (2021), 10; 1491. https://doi.org/10.3390/biom11101491
Olszewska-Czyz, Iwona; Kralik, Kristina; Prpić, Jelena

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Olszewska Czyz, I., Kralik, K. i Prpić, J. (2021). Biomolecules in Dental Applications: Randomized, Controlled Clinical Trial Evaluating the Influence of Hyaluronic Acid Adjunctive Therapy on Clinical Parameters of Moderate Periodontitis. Biomolecules, 11. (10). doi: 10.3390/biom11101491

Olszewska Czyz, Iwona, et al. "Biomolecules in Dental Applications: Randomized, Controlled Clinical Trial Evaluating the Influence of Hyaluronic Acid Adjunctive Therapy on Clinical Parameters of Moderate Periodontitis." Biomolecules, vol. 11, br. 10, 2021. https://doi.org/10.3390/biom11101491

Olszewska Czyz, Iwona, Kristina Kralik i Jelena Prpić. "Biomolecules in Dental Applications: Randomized, Controlled Clinical Trial Evaluating the Influence of Hyaluronic Acid Adjunctive Therapy on Clinical Parameters of Moderate Periodontitis." Biomolecules 11, br. 10 (2021). https://doi.org/10.3390/biom11101491

Olszewska Czyz, I., Kralik, K. i Prpić, J. (2021) 'Biomolecules in Dental Applications: Randomized, Controlled Clinical Trial Evaluating the Influence of Hyaluronic Acid Adjunctive Therapy on Clinical Parameters of Moderate Periodontitis', Biomolecules, 11(10). doi: 10.3390/biom11101491

Olszewska Czyz I, Kralik K, Prpić J. Biomolecules in Dental Applications: Randomized, Controlled Clinical Trial Evaluating the Influence of Hyaluronic Acid Adjunctive Therapy on Clinical Parameters of Moderate Periodontitis. Biomolecules [Internet]. 2021. [pristupljeno 10.05.2024.];11(10). doi: 10.3390/biom11101491

I. Olszewska Czyz, K. Kralik i J. Prpić, "Biomolecules in Dental Applications: Randomized, Controlled Clinical Trial Evaluating the Influence of Hyaluronic Acid Adjunctive Therapy on Clinical Parameters of Moderate Periodontitis", Biomolecules, vol. 11, br. 10, 2021. [Online]. Dostupno na: https://urn.nsk.hr/urn:nbn:hr:271:067440. [Citirano: 10.05.2024.]

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Podaci o radu
Naslov (engleski)Biomolecules in Dental Applications: Randomized, Controlled Clinical Trial Evaluating the Influence of Hyaluronic Acid Adjunctive Therapy on Clinical Parameters of Moderate Periodontitis
AutorIwona Olszewska-Czyz
AutorKristina Kralik
AutorJelena Prpić
Autorova ustanovaSveučilište u Rijeci
(Fakultet dentalne medicine)
Znanstveno / umjetničko
područje, polje i grana		BIOMEDICINA I ZDRAVSTVO
Dentalna medicina
Parodontologija
Sažetak (engleski)
The biological activity of hyaluronic acid (HA) has been well-researched during the past decades ; however, there are few randomized, controlled trials of its clinical effects in periodontal therapy. The purpose of this study was to evaluate the effect of hyaluronic acid on the principal parameters of periodontal healing. A specific, commercially available formulation designed and registered for professional dental application, composed of 16 mg/mL of cross-linked and 2 mg/mL of non-cross-linked HA, was used as an adjunctive to non-surgical periodontal therapy, and clinical parameters were evaluated after 3 months. The addition of HA to periodontal therapy demonstrated more favorable clinical results regarding reduction in inflammation, measured by bleeding on probing (−6% compared to the control group) and gain in periodontal attachment (1 mm more than control group), while it had no effect on probing depth reduction. No side effects were reported. Our study demonstrated that HA is a safe and easy-to-use biological agent ; due to its wide array of properties, it may significantly improve the results of periodontal therapy. However, more long-term studies are needed to investigate whether these favorable effects remain over time.
Ključne riječi (engleski)
Jezikengleski
Vrsta publikacijeZnanstveni rad - Izvorni znanstveni rad
Status objaveObjavljen
Vrsta recenzijeRecenziran - međunarodna recenzija
Verzija publikacijeObjavljena verzija rada (izdavačev PDF)
Naslov časopisaBiomolecules
Brojčani podacivol. 11, br. 10, 1491
p-ISSN2218-273X
DOIhttps://doi.org/10.3390/biom11101491
URN:NBNurn:nbn:hr:271:067440
Datum objave publikacije2021
URL dokumentahttp://bib.irb.hr/1224264
Vrsta resursaTekst
Prava pristupaOtvoreni pristup
Uvjeti korištenjaIkona licence Imenovanje 4.0 međunarodna (CC BY 4.0)
Datum i vrijeme pohrane2023-01-23 07:49:15