prikaz prve stranice dokumenta The Central Role of the NAD+ Molecule in the Development of Aging and the Prevention of Chronic Age-Related Diseases: Strategies for NAD+ Modulation
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The Central Role of the NAD+ Molecule in the Development of Aging and the Prevention of Chronic Age-Related Diseases: Strategies for NAD+ Modulation
International Journal of Molecular Sciences, 24 (2023), 3; 2959. https://doi.org/10.3390/ijms24032959
Poljšak, Borut; Kovač, Vito; Špalj, Stjepan; Milisav, Irina

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Poljšak, B., Kovač, V., Špalj, S. i Milisav, I. (2023). The Central Role of the NAD+ Molecule in the Development of Aging and the Prevention of Chronic Age-Related Diseases: Strategies for NAD+ Modulation. International Journal of Molecular Sciences, 24. (3). doi: 10.3390/ijms24032959

Poljšak, Borut, et al. "The Central Role of the NAD+ Molecule in the Development of Aging and the Prevention of Chronic Age-Related Diseases: Strategies for NAD+ Modulation." International Journal of Molecular Sciences, vol. 24, br. 3, 2023. https://doi.org/10.3390/ijms24032959

Poljšak, Borut, Vito Kovač, Stjepan Špalj i Irina Milisav. "The Central Role of the NAD+ Molecule in the Development of Aging and the Prevention of Chronic Age-Related Diseases: Strategies for NAD+ Modulation." International Journal of Molecular Sciences 24, br. 3 (2023). https://doi.org/10.3390/ijms24032959

Poljšak, B., et al. (2023) 'The Central Role of the NAD+ Molecule in the Development of Aging and the Prevention of Chronic Age-Related Diseases: Strategies for NAD+ Modulation', International Journal of Molecular Sciences, 24(3). doi: 10.3390/ijms24032959

Poljšak B, Kovač V, Špalj S, Milisav I. The Central Role of the NAD+ Molecule in the Development of Aging and the Prevention of Chronic Age-Related Diseases: Strategies for NAD+ Modulation. International Journal of Molecular Sciences [Internet]. 03.02.2023. [pristupljeno 02.05.2024.];24(3). doi: 10.3390/ijms24032959

B. Poljšak, V. Kovač, S. Špalj i I. Milisav, "The Central Role of the NAD+ Molecule in the Development of Aging and the Prevention of Chronic Age-Related Diseases: Strategies for NAD+ Modulation", International Journal of Molecular Sciences, vol. 24, br. 3, Veljača 2023. [Online]. Dostupno na: https://urn.nsk.hr/urn:nbn:hr:271:479593. [Citirano: 02.05.2024.]

Za citiranje koristite ovu mrežnu adresu: https://urn.nsk.hr/urn:nbn:hr:271:479593
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Naslov (engleski)The Central Role of the NAD+ Molecule in the Development of Aging and the Prevention of Chronic Age-Related Diseases: Strategies for NAD+ Modulation
AutorBorut Poljšak
AutorVito Kovač
AutorStjepan Špalj
AutorIrina Milisav
Autorova ustanovaSveučilište u Rijeci
(Fakultet dentalne medicine)
Znanstveno / umjetničko
područje, polje i grana		BIOMEDICINA I ZDRAVSTVO
Dentalna medicina
Sažetak (engleski)
The molecule NAD+ is a coenzyme for enzymes catalyzing cellular redox reactions in several metabolic pathways, encompassing glycolysis, TCA cycle, and oxidative phosphorylation, and is a substrate for NAD+-dependent enzymes. In addition to a hydride and electron transfer in redox reactions, NAD+ is a substrate for sirtuins and poly(adenosine diphosphate–ribose) polymerases and even moderate decreases in its cellular concentrations modify signaling of NAD+-consuming enzymes. Age-related reduction in cellular NAD+ concentrations results in metabolic and aging-associated disorders, while the consequences of increased NAD+ production or decreased degradation seem beneficial. This article reviews the NAD+ molecule in the development of aging and the prevention of chronic age-related diseases and discusses the strategies of NAD+ modulation for healthy aging and longevity.
Ključne riječi (engleski)
Jezikengleski
Vrsta publikacijeZnanstveni rad - Pregledni rad
Status objaveObjavljen
Vrsta recenzijeRecenziran - međunarodna recenzija
Verzija publikacijeObjavljena verzija rada (izdavačev PDF)
Naslov časopisaInternational Journal of Molecular Sciences
Brojčani podacivol. 24, br. 3, 2959
e-ISSN1422-0067
DOIhttps://doi.org/10.3390/ijms24032959
URN:NBNurn:nbn:hr:271:479593
Datum objave publikacije2023-02-03
URL dokumentahttps://www.mdpi.com/1422-0067/24/3/2959
Vrsta resursaTekst
Prava pristupaOtvoreni pristup
Uvjeti korištenjaIkona licence Imenovanje 4.0 međunarodna (CC BY 4.0)
Datum i vrijeme pohrane2023-05-17 11:14:35